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In the United Statesthe labeling of letrozole already warned that it had been associated with birth defectsNovartis has never sought FDA approval to market letrozole as a fertility medication and was clearly concerned about their liability if given in pregnancy.

Clomidclomipheneis an oral medication used for stimulating ovulationClomid is prescribed to stimulate ovulation in women with ovulatory dysfunction who are not pregnantdo not have abnormal bleeding or ovarian cystsand have normal liver functionIt binds to estrogen receptors in the hypothalamuspituitary glandovaryendometriumvaginaand cervixIt causes production of hormonesgonadotropinsby the pituitarywhich stimulates ovulation.

Store this medication at room temperature in the original containerIf you prefer to use a pillboxdiscuss this with your oncology pharmacistAsk your oncology team where to return any unused medication for disposalDo not flush down the toilet or throw in the trashKeep containers out of reach of children and pets.

Femara is authorised in the EU via national proceduresThis has led to divergences across Member States in the way the medicine can be usedas seen in the differences in the summaries of product characteristicsSmPCslabelling and package leaflets in the countries where the medicine is marketed.

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